100 days achievements of Dr. D. P. Rastogi Central Research Institute of Homoeopathy, Noida

Noida: The DDPRCRI(H), NOIDA has been in the fore front of patient care and researches in Homoeopathy for the last 17 years. The institute has been established with its focus on research and engaged for overall development and promotion of Homoeopathic system of medicine through scientific research. 

There is full-fledged hospital set up including OPD, IPD, Laboratory facilities, USG and imaging along with specialty clinics viz. ENT, Ophthalmology, Lifestyle Disorders, Physiotherapy, and Infertility clinic running successfully within the institute providing treatment facility to approx. 1 lakh patients annually in various conditions like sinusitis, Uterine fibroids, PCOS Fibroadenoma breast ,UTI Psoriasis, Osteoarthritis, Rheumatoid arthritis, urolithiasis, Bronchial asthma, Haemorrhoids Leukoderma, Hypothyroidism, BPH, post-COVID-19 syndrome etc.

Apart from catering to the needs of the patients, the institute carries out research in the field of Drug Standardisation, Drug Proving, Clinical Verification and Clinical Research.

As on date 45 clinical research studies has been undertaken since inception by the institution in various conditions with approx. 80 research articles/papers have been published in peer reviewed and indexed journals. Also, clinical trials on more than 25 disease conditions like Infertility, menstrual disturbances in adolescent girls, dysmenorrhoea, Stress incontinence of urine, Allergic rhinitis, Chronic urticaria, are being initiated for further research. 

 The Department of Drug Standardization at the institute focuses on improving the quality and authenticity of medicinal plants and medicines used in homeopathy. It conducts research to enhance homeopathic pharmacopoeial monographs and works on new research areas. The institute has state-of-the-art laboratories, an animal house for testing medicines, and conducts pharmacognostic profiles, physicochemical profiles, and toxicity and therapeutic studies on laboratory animals as part of pharmacological profile of homoeopathic medicines. The department has signed  3 Memoranda of Understanding (MoUs) with different universities and undergone a final assessment for NABL 17025, enhancing research capabilities and quality.  We are also working on a pharmacovigilance program for homeopathic medicines, focusing specifically on adverse effects and misleading advertisements.
Time to time various awareness activities as well as sensitization program such as Blood donation camp, Nasha Mukt Bharat Abhiyan, Swachhta Abhiyan, Poshan Abhiyan and Hindi Pakhwada, vigilance awareness campaign etc. are taken up by the institution.

100 days achievements of Dr. D. P. Rastogi Central Research Institute for Homoeopathy, Noida, under Ministry of Ayush

BACKGROUND 
(Dr Shaji Kumar, RO(H)/Scientist-4, Officer-In-Charge begin the addressed to media with background of the institute.)

The DDPRCRI(H), NOIDA has been in the fore front of patient care and researches in Homoeopathy for the last 17 years.

Central Research Institute of Homoeopathy located at A-1/1, Sector 24, NOIDA, Uttar Pradesh, one of the premier research institutes of Central Council for Research in Homoeopathy, New Delhi under Ministry of AYUSH, Govt. of India, came into existence on 1stMay, 2007. It was named as Dr. D.P. Rastogi Central Research Institute of Homoeopathy on 7th October 2015.

The institute has been established with its focus on research and engaged for overall development and promotion of Homoeopathic system of medicine through scientific research. There is full-fledged hospital set up including OPD, IPD, and Laboratory facilities along with specialty clinics viz. ENT, Ophthalmology, Lifestyle Disorders, Physiotherapy, and Infertility clinic running successfully within the institute. Apart from catering to the needs of the patients, the institute carries out research in the field of Drug Standardisation, Drug Proving, Clinical Verification and Clinical Research.
 

THE VISION
Undertaking Drug Development in Homoeopathy and validating them for clinical application while promoting them for use in mainstream health care.

THE MISSION
To prepare homoeopathic drugs by maintaining quality standards (GMP guideline) and proving on healthy human being by drug proving.
Verify the medicine through Clinical Verification and apply medicine on clinical cases.
Provide outstanding patient care services and develop treatment protocols on clinical conditions recommending use by the profession for public benefit.

PRESENT INFRASTRUCTURE
(Dr Padmalaya Rath, RO(H)/Scientist-3, Hospital In-Charge Spoke about existing infrastructure of the institute including Hospital, OPD, IPD, Laboratory facilities etc.)
The institute is a branch of Central Council for Research in Homoeopathy and has been functional since 1st May 2007. The Ground floor houses the Office of the In-charge, Reception/ Registration Counters, OPDs, waiting hall for  patients, Pharmacy, Labs etc.  The First floor houses the Pathology lab, IPD, Committee Room, etc, while the Second floor houses the Drug Standardisation Lab, Molecular Microbiology Lab, Zebrafish Lab and the Museum. The exterior of the building is decorated with many medicinal plants used in Homoeopathy. The staff strength of the institute including regular and contractual are 141. (49 are regular staff and 92 are contractual staff). 
Hospital Wing - The interior of the institute is compartmentalized into various parts, including Outdoor and Indoor Patient Departments (OPD & IPD), Research and Development (R&D) Wing, Laboratories for various investigations and imaging. The hospital follows NABH guideline.

Out-Patient Department (OPD)-The institute is running daily General OPDs and Research OPDs providing treatment to about 500-600 patients per day and approximately 27,000 patients have visited the  OPDs in last 3 months.

In OPD patients with disease condition such as anaemia, Flu like illness, dengue, chikungunya, worm infestation, Osteoarthritis, Rheumatoid Arthritis, Stress incontinence of Urine, BPH, Hypothyroidism, Diabetes, Hypertension, menstrual disorders, PCOS, Infertility, various skin condition, anxiety etc are provide treatment. 
Specialty Clinics on 
Lifestyle Disorders 
Infertility Clinic
ENT 
Ophthalmology 
Physiotherapy 
In-Patient Department (IPD)-The 35 bed (including female and male) IPD wing of the institute started operating from 7th August 2008. Patients suffering with various disease conditions like respiratory ailments, gastro-intestinal conditions, psoriasis, arthritis, allergic conditions, paediatric condition, post COVID-19 syndrome, other auto immune conditions etc. are being treated in IPD wing.
Laboratory Facilities
The Institute has functioning NABL accredited Pathology Laboratory, Biochemistry Laboratory with following test facility:
Complete Haemogram
Lipid profile, Diabetic profile, Thyroid profile, KFT, LFT, Serum Ca, Serum Phos, Dengue (NS1, IgM, IgG), Vitamin D3,Vitamin B12 RA factor, ANA, CRP, VDRL, Malaria, Widal test , hormonal profile etc.
Urine and Stool examinations
Other Investigation facilities 
Digital X-Ray
Ultrasound (USG)
ECG
Other facilities available
Library: Wherein various journal, medical books, latest research in field of homeopathy are available.

RESEARCH ACTIVITIES OF THE INSTITUTE
DRUG STANDARDIZATION PROGRAM

Dr. Pankaj Gupta, Assistant Director (Pharmacology), DS In-charge spoke about Drug standardization, Pharmacovigilance, Publication etc.)
The Department of Drug Standardization refines the quality, authenticity, and scientific validity of medicinal plants, as well as medicines (mother tinctures) used in homeopathy. The objective of this department is to conduct research to enhance the quality of homeopathic pharmacopoeial monographs and to work on new research projects. The department plays a leading role in advanced research and studies in the field of homeopathic medicine. The department have State of Art laboratories, including those for pharmacognosy, chemistry, zebrafish, pharmacology, microbiology, molecular biology, and an in-house pharmacy. Additionally, the institute has facilities like an animal house for testing homeopathic medicines.

In the botany department, complete pharmacognostic profiles are prepared through botanical surveys, identification, botanical authentication, and both macroscopic and microscopic testing. The chemistry department evaluates purity using various chromatographic and spectroscopic techniques, as well as physicochemical profiles, heavy metal profiling, and pesticide residue testing to ensure the quality of plants and homeopathic medicines. The pharmacology department conducts assessments of microbial contamination, toxicity testing in experimental animals, and therapeutic evaluations. Currently, there are four ongoing projects in the botany and chemistry departments. In the ongoing DNA barcoding project in the botany department, DNA barcodes for two medicinal plants have been created, and standards for six medicinal plants have been prepared in the image atlas and four in the HPTLC atlas, benefiting various researchers, Homoeopathic medicine manufacturers, the pharmaceutical industry, and students. Additionally, the Department of Drug Standardization is developing standards for medicinal plants for the Bureau of Indian Standards (BIS), focusing on five medicinal plants over the past 100 days, with BIS standards for two plants set to be published soon.

In the pharmacology department, various research projects are underway, including studies on the effects of homeopathic medicines on pain in zebrafish, the safety of homeopathic medicines in laboratory animals, toxicity testing of medicines on zebrafish embryos, and the effects of homeopathic medicines against multi-drug resistance in urinary infections. We have also initiated work on the effects of homeopathic medicines on arthritis in laboratory animals.

MoUs: Recently, we signed three Memoranda of Understanding (MoUs)—two at the CCRH headquarters level with SRM and Lucknow University, and one at the institutional level with Manywar Kashi Ram Degree College—to promote research. Under this, BSc students will receive training in various scientific techniques.
NABL 17025:Recently, labs underwent a final assessment for NABL 17025, further enhancing the research capabilities and quality.
Pharmacovigilance: We are also working on a pharmacovigilance program for homeopathic medicines, focusing specifically on adverse effects and misleading advertisements.

Publications: Department has published several research papers in prestigious journals, including one recently accepted in the Brazilian Journal of Pharmaceutical Sciences. Furthermore, department provide excellent facilities and guidance to students and researchers of the institute, enabling them to gain experience and progress in their future careers
DRUG PROVING RESEARCH PROGRAMME
(Dr Shaji Kumar, RO(H)/Scientist-4, Officer-In-Charge spoke about drug proving programme, Clinical Verification, ongoing and published Clinical Research work .)

Institute is one of the Drug proving centers since 2007 which conducts Drug Proving Research Trials to record the signs and symptoms of coded drugs on healthy volunteers, in collaboration with Bakson Homoeopathic Medical College & Hospital, Greater Noida and Nehru Homoeopathic Medical College & Hospital, New Delhi. Since 2019, this center initiated Drug Proving Research trial in collaboration with Dr. B. R. Sur Homoeopathic Medical College and Research Center, New Delhi. 
Proved drugs have been published in Peer reviewed journal and drug proving books has been published in various volumes by the council.

CLINICAL VERIFICATION
Verification of drugs give more reliability and helps us in creating an authentic Materia Medica. The institute has been conducting clinical verification studies of indigenous, rare and fragmentarily proved drugs since its inception in 1978. Some of these drugs were first proved by CCRH. Being a multicentric research study, DDPRCRIH, Noida has been a study site of clinical verification since 2007. 

Ongoing/ assigned: Clinical verification of 10 homoeopathic drugs- A multi-centric prospective interventional single arm clinical trial.

CLINICAL RESEARCH
The institute has carried out Clinical Research trials on various disease conditions. Till date 45 clinical research studies has been undertaken by the institution in various conditions like sinusitis, Uterine fibroids, PCOS Fibroadenoma breast, UTI Psoriasis, Osteoarthritis, Rheumatoid arthritis, urolithiasis, Bronchial asthma, Haemorrhoids Leukoderma, Hypothyroidism, post-COVID-19 syndrome etc. approx. 80 research articles/papers have been published in peer reviewed and indexed articles.

Also, clinical trials on more than 25 disease conditions like Stress incontinence of urine, Allergic rhinitis, Chronic urticaria, Infertility, menstrual disturbances in adolescent girls are in pipeline for further research.

MAJOR CAMPAIGNS AND INITIATIVES
(Dr Padmalaya Rath, RO(H)/Scientist-3, Hospital In-Charge Spoke about various campaigns and abhiyan conducted/organized at the institute etc.)
Blood donation camp

On occasion of world blood donor day DDPR CRIH organised an awareness lecture  given to patients and general public on 'Importance of blood donation". Pledge taken by officers, staff, patients and public in OPD of institute. Free blood group testing camp for the employees, patients and for general public. Sensitization lectures were given to school children on anaemia. 

Nasha Mukt Bharat Abhiyan
All officers/ Officials took the pledge on “NASHA MUKT BHARAT ABHIYAN” organized at DDPRCRI (H), Noida in month of August. Also, institution doctors have taken lectures to sensitized the OPD patients on the adverse effect of addiction/substance abuse.

Swachhta Abhiyan
Swachhata Hi Seva 2024 Abhiyan was celebrated in the institute from 17th September 2024 to 1st October,2024 with the conduction of various activities such as Walkathon to create awareness regarding importance of cleanness, Swachhta awareness camps were organized for people of villages in the Gram Sabha, awareness lecture was conducted in schools which has sensitized more than 2500 school children. Various competition swachhta abhiyan like poster making, slogan writing etc. Now, activities under Swachhata special campaign 4.0 are on-going.
Awareness lectures on importance of Swachhta in day to day life were impacted to approx. 3000 patients visiting OPD and Safai Mitra Health Camp were organized for 150 safai mitra (cleaning and housekeeping staff) of nearby 7 offices and institutions. Various competitions such as Best out of waste, Rangoli making, and In-house Quiz were organised by DDPRCRI(H)Noida.

Poshan Abhiyan
Poshan Pakhwada was celebrated in the institute in the month of September 2024 with the conduction of following activities such as Awareness lectures on nutrition, balanced diet, were delivered to patients visiting the institute, Sensitization lectures were given to villagers,Yoga camp was conducted for school children, school children were screened for sign of anaemia and Webinar on role of Ayush to address anaemia was organized for school children.

Hindi Pakhwada
Hindi Pakhwada was organized in the institute from 14th -28th September 2024  to celebrated and promote the use of Hindi in official work. During this period, various competitions were organized. Prizes and certificates were also distributed to the winners. A Hindi workshop was organized in the institute for all the staff of the institute wherein rules and regulations related to Official Language Hindi were discussed.
Hindi Timahi Samiksha baithak
A total of 20 trainees were trained in different level of Hindi training programs organized by the Central Hindi Training Institute in CRIH, Noida.

MAJOR ACHIEVEMENTS
(Dr Shaji Kumar, RO(H)/Scientist-4, Officer-In-Charge spoke about major achievements of the institute in last 3 months.)

Dr. D.P. Rastogi Central Research Institute of Homoeopathy, Noida, has receive the NABL M(EL)T Certification on 12th August 2024. The recognition reflects the institute’s quality services in diagnostics and will improve confidence of all stakeholders involved. 
NABH accreditation of homoeopathic hospital has been accessed.
Continued Medical education program for Officers and Researchers:CME programme organized was organized for all the officers on “Management of infertility with homoeopathy” and “Hindi Quarterly Meeting” at DDPRCRI (H), Noida in month of August. 

National Pharmacovigilance Awareness Program Activity was held at the seminar hall of DDPRCRI (Noida) on 23rd September-2024 on observance of 4th Pharmacovigilance Awareness week from 17th -23rd September to encourage a healthy Adverse Drug Reaction (ADR) reporting culture, ensuring that healthcare professionals recognize the importance of monitoring drug safety.

The institute was awarded for its excellent work in Hindi by the Town Official Language Implementation Committee, Noida on 23rd August 2024.
Research articles on post-COVID-19, PCOS, infertility  etc. were published in peer reviewed journal.